What can we learn from recent meta-analyses?

In pain research, meta-analyses based on systematic review have encompassed multiple therapeutic options, including pharmacotherapy, neurostimulation, invasive therapy, psychotherapy and complementary treatments such as acupuncture. These analyses are considered the standard to summarize the results of multiple studies and are regularly used and updated particularly by Cochrane groups. Multivariate and network meta-analysis methods are also emerging in pain research and allow to simultaneously analyse multiple outcomes and treatments, thus providing direct treatment comparisons. This presentation will address the relevance of meta-analyses in pain research through recent examples of studies conducted in neuropathic pain, but will also show that therapeutic algorithms derived from these analyses may not always be easily applicable to real life therapeutic management.